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چاپ مقاله اعضای مرکز تحقیقات کودکان شهریور 1402

چاپ مقاله اعضای مرکز تحقیقات کودکان شهریور 1402

چاپ مقاله اعضای مرکز تحقیقات کودکان شهریور 1402

Authors
Houman Hashemian, Ziba Vazifedoost Saleh, Masoomeh Afzalipoor, Alireza Jafari
Publication date
2023/7/31
Journal
Archives of Pediatric Infectious Diseases
Volume
11
Issue
3
Publisher
Brieflands
Description
Background
 
Urinary tract infections (UTIs) are among the most common childhood infections and can lead to serious complications, such as hypertension and renal failure, if not diagnosed and treated promptly. The prompt initiation of appropriate empiric therapy in children with upper UTIs requires the identification of causative bacteria and their antibiotic resistance patterns.
Objectives
 
The aim of this study was to investigate the frequency and patterns of antibiotic resistance among uropathogenic bacteria causing UTIs in children under 3 years of age admitted to the 17th Shahrivar Hospital in Rasht, Iran.
Methods
 
A total of 259 children diagnosed with UTIs from 2014 to 2020 were admitted to our hospital and included in the study. The age, sex, clinical symptoms, urine analysis results, urine culture findings, and antibiogram of the patients were documented in a questionnaire. The data were then analyzed in SPSS software version 21.
Results
 
The mean age of the children was 4.9 ± 2.7 months. Boys comprised 53.3% of the patients. Escherichia coli was the most frequent cause of UTIs in the children (56.4%), followed by Klebsiella (33.2%). The highest resistance was related to cephalothin (77.1 %), cephalexin (77.1 %), ampicillin (78.8 %), and amoxicillin (100 %).
Conclusions
 
The most common uropathogenic bacterium causing UTIs in young children was E. coli, which showed sensitivity to ciprofloxacin, amikacin, gentamicin, nitrofurantoin, imipenem, ceftriaxone, and nalidixic acid. Accordingly, it is advisable to use aminoglycosides as the drugs of choice to treat UTIs in children under the age of 3 years. In the case of any contraindication, third …
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  • کد خبر : 111661
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