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چاپ مقاله اعضای مرکز تحقیقات کودکان 1402 دی

چاپ مقاله اعضای مرکز تحقیقات کودکان دی

چاپ مقاله در Journal of Comprehensive Pediatrics

Authors
Setila Dalili, Afagh Hassanzadeh Rad, Omid Salkhori, Shayan Dabbaghi, Mohammad-Mehdi Karambin, Hamidreza Badeli, Shahin Koohmanaee
Publication date
2024
Journal
Journal of Comprehensive Pediatrics
Volume
15
Issue
1
Publisher
Brieflands
Description
Background
 
Recent studies in humans show that increased uric acid predicts hyperinsulinemia and obesity.
Objectives
 
Our study aimed to investigate whether hyperuricemia and insulin levels predict hypertension in obese children.
Methods
 
This analytical cross-sectional study was conducted on the records of 161 obese children aged 5 to 15 years old based on the defined inclusion criteria. Children's blood pressure, height, weight, FBS (fasting blood sugar), HDL (high-density lipoprotein), LDL (low-density lipoprotein), TG (triglyceride), HbA1c (hemoglobin A1c), urine albumin, creatinine, insulin levels, and uric acid were measured. Data were analyzed by SPSS software. The significance level was considered P < 0.05.
Results
 
According to the data obtained from this study, the mean of SBP (systolic blood pressure) and DBP (diastolic blood pressure) in obese children with hyperuricemia was higher than in obese children without hyperuricemia. The average insulin in obese children and hypertension was higher than in obese children without hypertension, especially in males and the age group of 5 - 10 years. The levels of cholesterol and LDL in hypertensive males were higher than in those with hyperuricemia. HDL was higher in children without hyperuricemia than in children with hyperuricemia. The strongest predictors of uric acid were age (P < 0.001, B = 0.183), HbA1c (P = 0.014, B = 0.255), and cholesterol (P = 0.03, B = -0.007), respectively.
Conclusions
 
Based on this study, there is a relationship between uric acid levels and parameters such as obesity and blood pressure, and the findings showed that increased uric acid predicts …
Scholar articles
S Dalili, AH Rad, O Salkhori, S Dabbaghi… - Journal of Comprehensive Pediatrics, 2024
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  • کد خبر : 118474
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آخرین بروز رسانی : 1402/10/05 12:04